Tenecteplase (TNKase®)

The ideal option for Canadian patients is to have continued availability of tenecteplase. ISMP Canada is committed to supporting any steps that can be taken to help ensure availability of tenecteplase.

If tenecteplase is not available, the necessity of using an alternative medication and protocol introduces complexity. The following documents are shared to proactively prepare for a possible drug shortage.

DOCUMENTS:

Notice to Hospitals from Roche Canada - (English) - PDF
Avis aux hôpitaux de Roche Canada - (Français) - PDF
Re: Availability of Tenecteplase (TNKase®) 50 mg vials through the Health Canada Special Access Programme (SAP) - November 3, 2014.
Regarding Tenecteplase (TNKase®) Temporary Drug Shortage: Considerations from Canadian Cardiology and Emergency Medicine Health Care Providers (HCPs)
- Tenecteplase (TNKase®) Guidance - (English) - PDF
- Directive sur Tenecteplase (TNKase®) - (Français) - PDF
Activase® AMI Dosing and Administration Instructional Videos available at: www.activase.ca
Note: A healthcare professional licence number is needed to access the site.

Example documents from external organizations

The documents displayed were prepared by individual named hospitals solely for internal use. These hospitals have authorized ISMP Canada to post this material as examples only. These materials are shared with the understanding that the named hospitals accept no responsibility for its use by any person who is not a staff member of, patient at, or otherwise associated with their facility.

Alberta Health Services

Links

View Current and Resolved drug shortages:

drugshortages.ca

ISMP Canada Drug Shortage Bulletins:

Drug Shortages and Medication Safety Concerns - March 2012

Ethical Framework:

Ethical Framework for Resource Allocation During the Drug Supply Shortage

The Drug Shortage Safety Knowledge Exchange was developed for the purpose of sharing learning experiences to help mitigate risks associated with drug shortages. Our collaborative goal is to support implementation of protocols, preventative strategies and system safeguards to decrease the risk for medication errors and to promote medication safety. To contribute documents and change management-related information to this site, email us at info@ismp-canada.org or phone us at 416-733-3131.

All reasonable precautions have been taken by the Institute for Safe Medication Practices Canada (ISMP Canada) to verify the information contained in this website. However, ISMP Canada does not guarantee the quality, accuracy, completeness or timeliness of such information. Accordingly, the information is shared without warranty or representation of any kind (express, implied or statutory). The responsibility for the interpretation and use of the information provided hereby lies with the reader. In no event shall ISMP Canada be liable for damages arising from the use or misuse of such information.