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ISMP Canada News

February 5, 2015: Change in Methadone Concentration Results in an Overdose in a Post-Partum Patient

Methadone is a potent synthetic opioid analgesic that has been used for decades, in conjunction with supportive psychological and social services, to manage and treat addiction to other opioids. This bulletin describes an incident involving a 10-fold overdose of methadone associated with a changeover of a hospital’s supply from methadone 1 mg/mL to a newly available 10 mg/mL product.  Read more...