September 9, 2015: ALERT - Methylene Blue Interaction Leads to Serotonin Syndrome
Indigo carmine, a marker dye often used in cystoscopy and in ureteral and other operative procedures, was recently discontinued. Some Canadian healthcare facilities have started to use methylene blue as a replacement. ISMP Canada received a report of serotonin syndrome experienced by a patient who was taking paroxetine and who received methylene blue for a procedure. As a result of an interaction between the 2 products, the patient required intubation and admission to the intensive care unit. Read more...
